“If you are mentally healthy, it is generally agreed upon that you are of sound mind and body, with, I think, a good self-image and a sense of self-worth, you don’t have a family history of schizophrenia or manic depression, I would be open to careful, probably supervised, use or experimentation with LSD,” Bourdain says. “I always found it useful to be around someone with previous experience, when doing it, in an environment you feel safe and controllable.”